L-Tyrosine
L-Tyrosine a promising cognitive enhancer.
Dutch researchers conducting a meta-analysis on L-tyrosine concluded that this amino acid “is a promising cognitive enhancer”
Blood levels of L-Tyrosine may be linked to quality of life
A 2004 study found that “normal tyrosine concentrations, compared to increased tyrosine concentrations, may be associated with fatigue and diminished quality of life.”
Specifically, they reported that Physical Functioning, Role Functioning Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role Emotional Functioning, and Mental Health all increased as tyrosine levels increased.
L-Phenylalanine
L-Phenylalanine (and L-Tyrosine) leads to increased alertness and arousal.*
A peer-reviewed paper published in 2008 concluded that L-Tyrosine and L-Phenylalanine are precursors to the neurotransmitter and that “dietary supplements that contain tyrosine and/or phenylalanine lead to alertness and arousal”
Vitamin B6
Vitamin B6 a rate-limiting substrate for dopamine production.
Research shows that “the role of vitamin B6 in amino acid metabolism makes it a rate limiting cofactor in the synthesis of neurotransmitters such as dopamine, serotonin, and GABA” [4]*
Vitamin B6 supports healthy immune function and metabolism.
A pair of papers from 2012 and 2013 showed that “Vitamin B6 has a direct effect on immune function and gene transcription/expression and plays a role in brain glucose regulation.”
Vitamin B6 may support healthy neural cells.
A review of cognitive enhancement and prevention studies concluded that Vitamin B6 plays a crucial role in helping the body maintain normal, healthy cognition through the aging process.
Vitamin B12
Vitamin NMN supports healthy nerves and neural cell function.
A 2022 review of the roles of folate and Vitamin NMN and their impact on the nervous system highlighted the importance of NMN levels for healthy neuronal function.
The same 2022 study mentioned above shows that NMN is crucial for the maintenance of normal, healthy cognitive function and memory recall through one’s lifespan.
Folate
Folate Linked to DNA function and neuronal differentiation.
Folate contributes to the normal, healthy functioning of our brains. A 2007 study connected folate to “reactions in brain tissue” including “DNA stability, gene expression/transcription, neuronal differentiation, hippocampal development, and propagation of action potentials”.
Vitamin C
Vitamin C is a neuroprotective antioxidant.
A 2007 study and a 2009 meta-analysis report that Vitamin C is not only a powerful antioxidant, but that it is also a neuroprotective compound. By reducing oxidative stress and helping to remove metabolic waste, Vitamin C keeps brain cells “cleaner” and supports normal cell functioning.
Vitamin C prevents oxidation of vitamins, minerals and amino acids.*
Vitamin C is the primary antioxidant present in our bloodstream and it exerts its beneficial effects on our cells as well as other vitamins, minerals and amino acids.
Trimethylglycine
TMG improves body composition, muscle size, and endurance.
Commonly found in beets, spinach and shellfish, TMG or trimethylglycine is also known as Betaine.
Betaine has been used by many athletes and fitness enthusiasts as a natural ergogenic aid. A 2013 study published data supporting TMG’s ability to increase muscle size, work capacity (endurance) and body composition after 6 weeks of supplementation.
